Gene information
Official symbol MIR125B1
Official full name microRNA 125b-1
Gene type microRNA
Chromosome11q24.1
Alias symbolhsa-mir-125b-1
Previous symbolMIRN125B1
Gene familyMicroRNA MIR10/100 family
Resources
Entrez Gene 406911
HGNC HGNC:31506
Ensembl ENSG00000207971
UCSC uc010rzr.1
GO terms: 68 records
GO Description Category LogP Number of genes Detail
GO:0001818 negative regulation of cytokine production GO Biological Processes -48.9957481 97 More
GO:0001959 regulation of cytokine-mediated signaling pathway GO Biological Processes -13.0991884 33 More
GO:0001960 negative regulation of cytokine-mediated signaling pathway GO Biological Processes -11.0318814 22 More
GO:0002683 negative regulation of immune system process GO Biological Processes -26.6415063 77 More
GO:0003729 mRNA binding GO Molecular Functions -83.3296105 82 More
GO:0006417 regulation of translation GO Biological Processes -24.5257987 35 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0010720 positive regulation of cell development GO Biological Processes -17.713649 52 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0014013 regulation of gliogenesis GO Biological Processes -13.3514185 26 More
GO:0014015 positive regulation of gliogenesis GO Biological Processes -11.0528361 19 More
GO:0016441 post-transcriptional gene silencing GO Biological Processes -100 124 More
GO:0016525 negative regulation of angiogenesis GO Biological Processes -31.9326641 51 More
GO:0017148 negative regulation of translation GO Biological Processes -31.7864246 33 More
GO:0030371 translation repressor activity GO Molecular Functions -100 82 More
GO:0030856 regulation of epithelial cell differentiation GO Biological Processes -15.4645914 35 More
GO:0030858 positive regulation of epithelial cell differentiation GO Biological Processes -9.94639997 18 More
GO:0031047 gene silencing by RNA GO Biological Processes -100 125 More
GO:0032680 regulation of tumor necrosis factor production GO Biological Processes -32.0729913 56 More
GO:0032720 negative regulation of tumor necrosis factor production GO Biological Processes -18.6356508 28 More
GO:0033674 positive regulation of kinase activity GO Biological Processes -29.8538991 87 More
GO:0034248 regulation of cellular amide metabolic process GO Biological Processes -28.1662419 40 More
GO:0034249 negative regulation of cellular amide metabolic process GO Biological Processes -35.7644618 37 More
GO:0035194 post-transcriptional gene silencing by RNA GO Biological Processes -100 124 More
GO:0035195 miRNA-mediated gene silencing GO Biological Processes -100 124 More
GO:0035278 miRNA-mediated gene silencing by inhibition of translation GO Biological Processes -46.1099674 32 More
GO:0038061 NIK/NF-kappaB signaling GO Biological Processes -4.66781085 9 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043549 regulation of kinase activity GO Biological Processes -36.8507249 123 More
GO:0045182 translation regulator activity GO Molecular Functions -97.0300828 82 More
GO:0045596 negative regulation of cell differentiation GO Biological Processes -26.9785067 101 More
GO:0045765 regulation of angiogenesis GO Biological Processes -63.6171248 109 More
GO:0045859 regulation of protein kinase activity GO Biological Processes -34.3615088 109 More
GO:0050678 regulation of epithelial cell proliferation GO Biological Processes -51.9930445 102 More
GO:0050680 negative regulation of epithelial cell proliferation GO Biological Processes -26.5961536 48 More
GO:0050767 regulation of neurogenesis GO Biological Processes -15.7439029 55 More
GO:0050769 positive regulation of neurogenesis GO Biological Processes -12.1167088 37 More
GO:0051147 regulation of muscle cell differentiation GO Biological Processes -17.2781401 19 More
GO:0051149 positive regulation of muscle cell differentiation GO Biological Processes -18.0749983 16 More
GO:0051150 regulation of smooth muscle cell differentiation GO Biological Processes -12.3730388 10 More
GO:0051152 positive regulation of smooth muscle cell differentiation GO Biological Processes -12.3879234 8 More
GO:0051347 positive regulation of transferase activity GO Biological Processes -26.6059528 90 More
GO:0051960 regulation of nervous system development GO Biological Processes -17.2202851 64 More
GO:0051962 positive regulation of nervous system development GO Biological Processes -13.2580156 43 More
GO:0060251 regulation of glial cell proliferation GO Biological Processes -8.90876897 12 More
GO:0060252 positive regulation of glial cell proliferation GO Biological Processes -5.51502780 7 More
GO:0060284 regulation of cell development GO Biological Processes -22.9455891 78 More
GO:0060759 regulation of response to cytokine stimulus GO Biological Processes -13.7003447 35 More
GO:0060761 negative regulation of response to cytokine stimulus GO Biological Processes -10.5179624 22 More
GO:0070103 regulation of interleukin-6-mediated signaling pathway GO Biological Processes -5.92711729 4 More
GO:0070104 negative regulation of interleukin-6-mediated signaling pathway GO Biological Processes -6.51405684 4 More
GO:0071396 cellular response to lipid GO Biological Processes -37.0669488 98 More
GO:1901342 regulation of vasculature development GO Biological Processes -64.8504074 111 More
GO:1901343 negative regulation of vasculature development GO Biological Processes -32.5354692 52 More
GO:1902106 negative regulation of leukocyte differentiation GO Biological Processes -7.27922558 19 More
GO:1902947 regulation of tau-protein kinase activity GO Biological Processes -4.91299256 6 More
GO:1903231 mRNA base-pairing post-transcriptional repressor activity GO Molecular Functions -100 82 More
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -32.3948799 57 More
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production GO Biological Processes -18.2876323 28 More
GO:1903707 negative regulation of hemopoiesis GO Biological Processes -7.72888419 20 More
GO:1904892 regulation of receptor signaling pathway via STAT GO Biological Processes -12.9980471 24 More
GO:1904893 negative regulation of receptor signaling pathway via STAT GO Biological Processes -5.45308560 5 More
GO:1905063 regulation of vascular associated smooth muscle cell differentiation GO Biological Processes -11.0911570 8 More
GO:1905065 positive regulation of vascular associated smooth muscle cell differentiation GO Biological Processes -9.45869795 6 More
GO:2000112 regulation of cellular macromolecule biosynthetic process GO Biological Processes -24.0725356 37 More
GO:2000113 negative regulation of cellular macromolecule biosynthetic process GO Biological Processes -32.997895 35 More
GO:2000181 negative regulation of blood vessel morphogenesis GO Biological Processes -32.6997315 52 More
KEGG pathways: 1 record
KEGG Description Category LogP Number of genes Detail
hsa05206 MicroRNAs in cancer KEGG Pathway -100 81 More
Related studies: 2 records
Molecular factor Omics type Application Objective MI type Reference
hsa-miR-125b-5p transcriptomics good predictor acute myocardial infarction[diagnosis] acute myocardial infarction Huang S et al. Circ Cardiovasc Genet. 2014
hsa-miR-125b-5p transcriptomics excellent predictor acute myocardial infarction[diagnosis] acute myocardial infarction Jia K et al. Mol Med Rep. 2016
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